Dr. Juan Ding

Boston Eye Blink is founded by Juan Ding, OD, PhD. Dr. Ding currently works at UMass Memorial Medical Center in Worcester MA as an attending optometrist and an assistant professor of UMass Medical School. Dr. Ding specializes in comprehensive eye exams for adults and children, diabetic eye exams, refraction, contact lens fitting, and binocular visual dysfunctions.

Dr. Ding received her PhD in Molecular and Cellular Biology from Ohio University, and OD from New England College of Optometry. Dr. Ding graduated top of her class from New England College of Optometry with the William R. Baldwin Scholastic Achievement Award in 2017. She was the recipient of 2016 Dr. Norman E. Wallis Award for Excellence (This award is given to the candidate who receives the highest score on the main Part I Applied Basic Science Examination in National Board of Examiners in Optometry), 2016 Charles Robert Soltes Scholarship, and 2016 NECO Alumni Scholarship.

Dr. Ding completed a post-doctoral research fellowship specializing in dry eye disease at Schepens Eye Research Institute (SERI) /Massachusetts Eye and Ear (MEE) of Harvard Medical School, before becoming Investigator at SERI and Instructor in Ophthalmology at MEE/Harvard Medical School. Dr. Ding’s primary research interest focuses on hormonal influence of dry eye disease and corneal wound healing, for which she received numerous awards and grants to conduct research, including 2011 ARVO Foundation for Eye Research/Vistakon Dry Eye Fellowship Award, 2014 National Eye Institute K99 Pathway to Independence Award, and 2015 Pfizer Young Investigator in Endocrinology Award.

Dr. Ding enjoys seeing patients, and is interested in promoting patient awareness and education of eye conditions and diseases. Dr. Ding is a member of the Tear Film and Ocular Surface Society, which is a non-profit organization that brings scientists, clinicians and industry professionals together to seek action needed to help the world see better.

 Here is a list of Dr. Ding’s publications (selected):

  1. Tiong, J. D., Gosney, E., Ding, J., Chin, E. & Kopchick, J. J. (2006). A liver specific gene that is expressed in growth hormone transgenic mice and in normal female mice as a function of age. Growth Horm IGF Res 16, 145-56. PMID: 16723264
  2. Kopchick, J. J., Sackmann-Sala, L. & Ding, J. (2007). Primer: molecular tools used for the understanding of endocrinology. Nature Reviews Endocrinology 3, 355-368. PMID: 17377618
  3. List, E. O., Berryman, D. E., Bower, B., Sackmann-Sala, L., Gosney, E., Ding, J., Okada, S. & Kopchick, J. J. (2008). The use of proteomics to study infectious diseases. Infect Disord Drug Targets 8, 31-45.
  4. Sackmann-Sala, L., Ding, J., Frohman, L. A. & Kopchick, J. J. (2009). Activation of the GH/IGF-1 axis by CJC-1295, a long-acting GHRH analog, results in serum protein profile changes in normal adult subjects. Growth Hormone & IGF Research 19, 471-477.
  5. Ding, J., List, E. O., Okada, S. & Kopchick, J. J. (2009). Perspective: Proteomic approach to detect biomarkers of human growth hormone. Growth Hormone & IGF Research 19, 399-407.
  6. Ding, J. & Kopchick, J. J. (2011). Plasma biomarkers of mouse aging. Age (Dordr) 33, 291-307.
  7. List, E. O., Sackmann-Sala, L., Berryman, D. E., Funk, K., Kelder, B., Gosney, E. S., Okada, S., Ding, J., Cruz-Topete, D. & Kopchick, J. J. (2011). Endocrine parameters and phenotypes of the growth hormone receptor gene disrupted (GHR-/-) mouse. Endocrine Reviews 32, 356-86.
  8. Ding, J., Berryman, D. E. & Kopchick, J. J. (2011). Plasma proteomic profiles of bovine growth hormone transgenic mice as they age. Transgenic Research 20, 1305-20.
  9. Ding, J., List, E. O., Bower, B. D. & Kopchick, J. J. (2011). Differential effects of growth hormone versus insulin-like growth factor-I on the mouse plasma proteome. Endocrinology 152, 3791-802.
  10. Ding, J., Okada, S., Jorgensen, J. O. & Kopchick, J. J. (2011). Novel serum protein biomarkers indicative of growth hormone doping in healthy human subjects. Proteomics 11, 3565-71.
  11. Ding, J., Berryman, D. E., Jara, A. & Kopchick, J. J. (2012). Age- and sex-associated plasma proteomic changes in growth hormone receptor gene-disrupted mice. Journals of Gerontology. Series A, Biological Sciences and Medical Sciences 67, 830-40.
  12. Liu, Y., Cao, Y., Zhang, W., Bergmeier, S., Qian, Y., Akbar, H., Colvin, R., Ding, J., Tong, L., Wu, S., Hines, J. & Chen, X. (2012). A small-molecule inhibitor of glucose transporter 1 downregulates glycolysis, induces cell-cycle arrest, and inhibits cancer cell growth in vitro and in vivo. Mol Cancer Ther 11, 1672-82.
  13. Ding, J., Sackmann-Sala, L. and Kopchick, J., Mouse models of growth hormone action and aging: A proteomic perspective, Proteomics. 2013 Feb;13(3-4):674-85.
  14. Ding, J & Sullivan, D. A. (2012). Aging and dry eye disease. Exp Gerontol 47, 483-90.
  15. LiuS, Kam WR, Ding J, Hatton MP, Sullivan DA, Effect of growth factors on the proliferation and gene expression of human meibomian gland epithelial cells, Invest Ophthalmol Vis Sci. 2013 Apr 5;54(4):2541-50.
  16. Ding, J., Kam, W., Dieckow, J., Sullivan, D.A., The influence of 13-cis Retinoic Acid on Human Meibomian Gland Epithelial Cells, Invest Ophthalmol Vis Sci. 2013 May 30. 54(6):4341-50, doi:pii: iovs.13-11863v1. 10.1167/iovs.13-11863.
  17. Ding, J., Sullivan, D. A. (2014), The effects of insulin-like growth factor-1 and growth hormone on human meibomian gland epithelial cells. JAMA Ophthalmology, 132(5):593-9
  18. Liu, Y., Kam, W. R., Ding, J., Sullivan, D. A., One man’s poison is another man’s meat Using azithromycin-induced phospholipidosis to promote ocular surface health. Toxicology, 2014 Mar 6;320C:1-5.
  19. David A. Sullivan, Yang Liu, Wendy R. Kam, Juan Ding, Karin M. Green, Scott A. Shaffer, Mark P. Hatton and Shaohui Liu, Serum-induced differentiation of human meibomian gland epithelial cells, Investigative ophthalmology & visual science, 2014, 55(6):3866-77
  20. Liu Y, Kam WR, Ding J, Sullivan DA. Effect of azithromycin on lipid
    accumulation in immortalized human meibomian gland epithelial cells. JAMA
    Ophthalmol. 2014 Feb;132(2):226-8.
  21. Yang Liu and Juan Ding, The combined effect of azithromycin and insulin-like growth factor-1 on cultured human meibomian gland epithelial cells, Invest Ophthalmol Vis Sci. 2014 Aug 14;55(9):5596-601. doi: 10.1167/iovs.14-14782.
  22. Juan Ding, Barbara Wirostko, David A. Sullivan, Human Growth Hormone Promotes Corneal Epithelial Cell Migration in Vitro, Cornea, 2015, PMID: 25782399
  23. Liu Y, Kam WR, Ding J, Sullivan DA. Can tetracycline antibiotics duplicate the ability of azithromycin to stimulate human meibomian gland epithelial cell differentiation? Cornea. 2015 Jan 21.
  24. Barbara Wirostko, MaryJane Rafii, David A. Sullivan, Julia Morelli, Juan Ding, Novel therapy to treat corneal epithelial defects: a hypothesis with growth hormone, The Ocular Surface, 2015, PMID:26045234
  25. Juan Ding, Yang Liu, David A Sullivan, Effects of Insulin and high glucose on cultured human meibomian gland epithelial cells, Invest Ophthalmol Vis Sci. 2015 Dec;56(13):7814-20
  26. Liu Y, Knop E, Knop N, Sullivan DA, List EO, Kopchick JJ, Kam WR, Ding J. Growth Hormone Influence on the Morphology and Size of the Mouse Meibomian Gland. J Ophthalmol. 2016;2016:5728071. doi: 10.1155/2016/5728071. Epub 2016 Feb 14
  27. Kam WR, Liu Y, Ding J, Sullivan DA. Do Cyclosporine A, an IL-1 Receptor
    Antagonist, Uridine Triphosphate, Rebamipide, and/or Bimatoprost Regulate Human Meibomian Gland Epithelial Cells? Invest Ophthalmol Vis Sci. 2016 Aug


Book Chapter

  • Ding J, Kopchick JJ (2011). Skeletal muscle. Laron Syndrome- From Man to Mouse (pp. 465-472). In Zvi Laron and John J. Kopchick (Eds.). Berlin: Springer